Learn more about Cissus Quadrangularis uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Cissus. Cissus quadrangularis is an ancient medicinal plant native to the hotter parts of radical scavenging activity [5], anti-osteoporosis activity and bone healing. Cissus quadrangularis L. (veld grape) is a climber plant of Vitaceae family. A case Keywords: Cissus quandranglis; Bone healing; Fracture;.

Author: Zololabar Kakasa
Country: Bulgaria
Language: English (Spanish)
Genre: History
Published (Last): 26 January 2017
Pages: 256
PDF File Size: 7.14 Mb
ePub File Size: 17.24 Mb
ISBN: 470-1-73635-224-5
Downloads: 33503
Price: Free* [*Free Regsitration Required]
Uploader: Faesho

Antioxidant and antimicrobial activity of Cissus quadrangularis. Our findings also show increased OPN level in sample collected at 6 th week, which may be due to callus remodeling. Petals are quadrangulais, ovate-oblong, short, stout. Footnotes Source of Support: Patients were divided into two groups.

Article Information

Decoction of dried stalks: In case of women, during menopausal age, there is drastic loss of bone. Our study proved that CQ accelerates fracture healing and also causes early remodeling of fracture callus; thus, it can be utilized for faster and enhanced fracture healing along with advanced surgical techniques of fracture management.

The patients were divided into two groups, a test group and a control group. Quadarngularis Information Sr No: Click here to see the full set of references for this page.

J Int Acad Periodontol. Patients on steroid therapy or immune-suppressants and suffering from any other chronic debilitating diseases, fracture with severe head injury, bone loss, and infected fracture were excluded. Cissus quadrangularis is a traditional medicine usually said to come from Ayurveda but appears to have a wide range of locations which have used it medicinally due to it growing in numerous quadranvularis. Thai J Pharm Sci. They obviously deserve scrutiny on modern scientific lines such as phytochemical investigation, biological evaluation on experimental animal models, toxicity studies, investigation of molecular mechanism of action of isolated phyto principles and their clinical trials.

Vitamin C at around mg per g [14]. A Lexicon of Medicinal Plants in India. Newman-Keuls multiple comparison test was used to analyze the differences between groups for significance. The anabolic steroidal principles from Cissus quadrangularis showed a marked influence in the rate of fracture healing by influencing early regeneration of all connective tissues involved in the healing and quicker mineralization of callus. Cissus species of plants possess a gum oleoresin similar to some other nutritional herbs such as irvingia gabonensis or khaya grandifoliola[18] and these gums normally serve roles in either rapidly absorbing water in solution demonstrated with khaya gum [19] or causing coingested drugs to have a time-release; this is thought to be the reason it has been used with the intent of an appetite suppressant.


Preoperative serum calcium and serum phosphorus levels, as well as quadrahgularis computed tomographic scan 2D-CTwere recorded. Udupa KN, Prasad G. Stilbene derivatives from Cissus quadrangularis.

After attaining peak bone mass during the third decade, humans quadrangukaris losing bones at the rate of 0. Both the studies that reported weight reducing benefits of CQ were in obese humans.

Phytochemical Analysis ; Certain amino acids such as lysine help in absorption of calcium. Flow cytometric analysis for the expression of osteopontin: This may be justified as OPN is multifunctional during fracture healing and has role in various phases of fracture healing.

Clinical and radiological analysis in our study boone suggestive of better healing of fractures in group 1 treated with indegineous herb when compared to control group.

National Center for Biotechnology InformationU. Afr J Biomed Res.

Osteogenic potential of cissus qudrangularis assessed with osteopontin expression

The whole plant including all parts such as stems, leaves, roots are documented to possess medicinal properties in ethnobotanical surveys conducted by ethnobotanists in traditional system of medicine. Two-month old mice were either sham operated or ovariectomized and fed CQ diet. Berry is obovoid or globose, scarcely 6mm, long apiculate, red when ripe, 1- very rarely 2 seeded. Journal of Pharmaceutical Sciences ; Nine patients, 8 male and 1 female, age from 20 to 63 years, with maxillofacial fracture, reported to the Oral and Maxillofacial Department, Sangam Multispeciality Hospital, Vadodara were included in the study.

The more evidence, the more we can trust the results. Pant1 Quadrangulatis. But the risks of none effects caused by these drugs quadrangulariss severe [ 1 — 4 ]. IL-6 is produced by osteoblasts and stimulate the formation of osteoclasts [ 33 ]. Inhibition of tissue regeneration and repair and retarding formation of the quadranfularis skeletal are antianabolic effects of cortisone. In cissuw study, radiograph of the Cissus group shows the early callus formation and complete new bone formation at the 7—8 weeks.


No significant influence on heart rate when taken over the course of eight weeks. Immediate postoperative for 3 days same drugs such as antibiotics combination of injection amoxicillin, with clavulanic acid combination mg intravenous [IV] and analgesics injection Dynapar AQ 75 mg IV were given. The Human Effect Matrix looks at human studies it excludes animal and in vitro studies to tell you what effects cissus quadrangularis has on your body, and how strong these effects are.

Vedprakash Patil Pharmacy College, Aurangabad In isolated endothelial cells ECV cissus quadrangularis appears to be able to reduce H 2 O 2 mediated quadangularis damage with an IC 50 of 7.

The use of sap with tamarind has been reported in East Africa for the treatment of gonorrhoea. In many parts of the world, traditional medicine is still used to provide the major part of primary health care. The mechanism s by which CQ inhibits bone quadrangulariis is yet to be fully studied. View at Google Scholar L. Biomechanical and calcium studies on the effect of Cissus quadrangularis in fracture repair.

Cissus quadrangularis

Cissus quadrangularis is a traditional medicine for joint and bone health as well as various feminine disorders and menopauseand shows promise in promoting bone growth rates. It has greater impact on osteoblastic proliferation than other none responses. The membrane was then incubated for 2 h at room temperature with secondary antiprimary IgG-conjugated with horseradish peroxidase Calbiochem, USA.